KPV
Immune & Inflammation · 10 mg fill · Research Peptide
The C-terminal tripeptide of alpha-MSH, studied for NF-κB and MAP-kinase pathway inhibition in cell models.
Overview
KPV is the naturally occurring C-terminal tripeptide of alpha-melanocyte-stimulating hormone (Lys-Pro-Val). It retains the anti-inflammatory signaling described for the parent hormone without its pigmentation activity. Cell-culture and rodent studies report inhibition of NF-κB and MAP-kinase signaling and reduced pro-inflammatory cytokine output. No controlled human trials exist. Supplied lyophilized for in-vitro research use.
Specifications
- Sequence
- Lys-Pro-Val · α-MSH C-terminal tripeptide
- Form
- Lyophilized powder
- Vial Size
- 10 mg
- Purity
- >99% (HPLC)
- Reconstitution
- Bacteriostatic water
- Storage
- −20°C · protect from light
- Documentation
- Batch-specific COA
Research applications
- NF-κB and MAP-kinase signaling assays
- Cytokine-production cell-culture studies
- Melanocortin-fragment structure–activity research
- PepT1 transporter uptake studies
For research use only. This product is intended for laboratory and educational research purposes only. It has not been evaluated by the FDA and is not for human or veterinary consumption, diagnosis, treatment, or cure of any condition.
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