5-Amino-1MQ
Metabolic · 50 mg fill · Research Peptide
A small-molecule NNMT inhibitor used as a research tool for probing nicotinamide methylation in cell culture.
Overview
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide. Because NNMT sits upstream of the NAD+ salvage pathway, the compound is used in vitro to probe NNMT activity and nicotinamide flux. The published record is limited and preclinical. Supplied for in-vitro research use.
Specifications
- Composition
- 5-amino-1-methylquinolinium · small-molecule NNMT inhibitor
- Form
- Lyophilized powder
- Vial Size
- 50 mg
- Purity
- >99% (HPLC)
- Reconstitution
- Bacteriostatic water
- Storage
- −20°C · protect from light
- Documentation
- Batch-specific COA
Research applications
- NNMT enzyme-inhibition assays
- Nicotinamide and NAD+ salvage-pathway research
- Methyl-donor flux studies in cell culture
- Small-molecule selectivity screening
For research use only. This product is intended for laboratory and educational research purposes only. It has not been evaluated by the FDA and is not for human or veterinary consumption, diagnosis, treatment, or cure of any condition.
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